AC-5216

Product Name: AC-5216
CAS No.: 226954-04-7
Chemical Name: AC-5216
Synonyms: CS-2606;AC-5216;XBD-173;Mapunil;EMapunil;AC-5216,XBD-173;Emapunil(AC-5216);AC 5216 (Emapunil);XBD173 >=98% (HPLC);AC-5216;XBD-173;EMAPUNIL;AC5216;AC 5216
CBNumber: CB32448636
Molecular Formula: C23H23N5O2
Formula Weight: 401.46
MOL File: 226954-04-7.mol

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AC-5216 Property

storage temp.: 2-8°C
solubility: DMF: 30 mg/mL; DMF:PBS (pH 7.2) (1:20): 0.05 mg/mL; DMSO: 5 mg/mL
form: powder
color: white to beige

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML1223
Product name: XBD173
Purity: ≥98% (HPLC)
Packaging: 5MG
Price: $118
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML1223
Product name: XBD173
Purity: ≥98% (HPLC)
Packaging: 25MG
Price: $462
Updated: 2024/03/01

Cayman Chemical

Product number: 18522
Product name: AC-5216
Purity: ≥98%
Packaging: 1mg
Price: $34
Updated: 2024/03/01

Cayman Chemical

Product number: 18522
Product name: AC-5216
Purity: ≥98%
Packaging: 5mg
Price: $109
Updated: 2024/03/01

Cayman Chemical

Product number: 18522
Product name: AC-5216
Purity: ≥98%
Packaging: 10mg
Price: $183
Updated: 2024/03/01

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AC-5216 Chemical Properties,Usage,Production

Uses

Emapunil possesses anxiolytic and antidepressant-like effects and a ligand for translocator protein (TSPO), which plays an important role in the depression treatment.

Biochem/physiol Actions

XBD173 (emapunil, AC-5216) is a potent and selective translocator protein 18 kDa (TSPO) ligand with a Ki value of 0.297 nM. XBD173 acts at the TSPO translocator protein, formerly called the peripheral benzodiazepine receptor, which is involved in production of neuroactive steroids such as allopregnanolone in the brain. TSPO carries cholesterol from the outer to the inner mitochondrial membrane, which is the rate-limiting step of steroidogenesis. XBD173 enhances GABA-mediated neurotransmission via induction of neurosteroidogenesis and exhibits anti-anxiety and antidepressant-like effects.

storage

Store at +4°C

AC-5216 Preparation Products And Raw materials

Raw materials

Preparation Products

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AC-5216 Suppliers

China 73 India 1 United Kingdom 3 United States 14 Global 91

Novachemistry

Tel: 44-20819178-90 02081917890
Fax: (0)2080432064
Email: info@novachemistry.com
Country: United Kingdom
ProdList: 4381
Advantage: 58

226954-04-7, AC-5216Related Search:

2-PHENYLPYRIMIDIN-5-AMINE AC-5216

EMapunil

XBD-173

N-Benzyl-N-ethyl-2-(7-Methyl-8-oxo-2-phenyl-7,8-dihydro-9H-purin-9-yl)acetaMide

9H-Purine-9-acetaMide,N-ethyl-7,8-dihydro-7-Methyl-8-oxo-2-phenyl-N-(phenylMethyl)-

AC 5216 (Emapunil)

N-Ethyl-7,8-dihydro-7-methyl-8-oxo-2-phenyl-N-(phenylmethyl)-9H-purine-9-acetamide

Emapunil(AC-5216)

AC-5216

CS-2606

AC-5216;XBD-173;EMAPUNIL;AC5216;AC 5216

XBD173 >=98% (HPLC)

9H-Purine-9-acetaMide,N-ethyl-7,8-dihydro-7-Methyl-8-oxoChemicalbook-2-phenyl-N-(phenylMethyl)-

Mapunil

N-benzyl-N-ethyl-2-(7-methyl-8-oxo-2-phenyl-7H-purin-9(8H)-yl)acetamide

PTSD,depression,T2DM,AC 5216,antianxiety,Emapunil,XBD 173,disorder,traumatic,MBR,neuroprotective,inhibit,post,XBD173,Antidepressant,AC5216,Inhibitor,stress,anti-inflammatory

AC-5216,XBD-173

226954-04-7

Inhibitors